Table 5 Examples of commercial nanoantiobiotics products
From: Design, challenge, and promise of stimuli-responsive nanoantibiotics
Company | Product | Composition | Current application | Development stage |
|---|---|---|---|---|
Insmed | Arikace | Liposomal amikacin | Chronic P. aeruginosa Infection | Clinical trial (phase 3) |
Staten Serum Institute | CAF09 | Cationic liposome-based adjuvant | Tuberculosis, HIV | Preclinical |
Smith & Nephew | Acticoat | Ag NP coated polyethylene mesh | Wound dressing | Marketed |
I-Flow | ON-Q silver soaker | Ag NP coated polyvinylchloride | Catheter for delivery of local anesthetics | Marketed |
Benanova | EbNP | Ag ions embedded in lignin | Nanosilver substitute | Marketed |
INGMedical | Antimicrobial textiles | Electrospun textiles with metallic NPs | Medical devices | Marketed |
NanoBio | NanoStat | Nanoemulsion based carrying various adjuvants | Intranasal/intramuscular vaccine delivery | Completed phase 1 |
IBM | – | Stimuli-responsive polymer hydrogel | Antimicrobial | Pre-clinical |