Skip to main content

Table 1 Particle size, polydispersity index, drug loading and entrapment efficiency of three batches of felodipine loaded nanoparticles (Data represents mean ± SD)

From: Felodipine loaded PLGA nanoparticles: preparation, physicochemical characterization and in vivo toxicity study

Batch Drug-polymer ratio Particle size (nm) ± SD (n = 3) Polydispersity index Drug loading (% w/w) Entrapment Efficiency (% w/w)
F1 1:2 307 ± 4.51 0.442 ± 0.098 12.43 ± 0.89 68.45 ± 0.869
F2 1:3 226 ± 5.39 0.216 ± 0.009 9.47 ± 0.12 85.28 ± 0.328
F3 1:4 273 ± 6.28 0.254 ± 0.004 8.83 ± 0.04 83.23 ± 0.365
  1. EE % w w = Weight of the drug in nanoparticle Weight of the polymer and drug added ×100.
  2. DL % w w = Weight of the drug in nanoparticle Weight of the polymer and drug added ×100.