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Nano Convergence

Table 1 Particle size, polydispersity index, drug loading and entrapment efficiency of three batches of felodipine loaded nanoparticles (Data represents mean ± SD)

From: Felodipine loaded PLGA nanoparticles: preparation, physicochemical characterization and in vivo toxicity study

Batch

Drug-polymer ratio

Particle size (nm) ± SD (n = 3)

Polydispersity index

Drug loading (% w/w)

Entrapment Efficiency (% w/w)

F1

1:2

307 ± 4.51

0.442 ± 0.098

12.43 ± 0.89

68.45 ± 0.869

F2

1:3

226 ± 5.39

0.216 ± 0.009

9.47 ± 0.12

85.28 ± 0.328

F3

1:4

273 ± 6.28

0.254 ± 0.004

8.83 ± 0.04

83.23 ± 0.365

  1. EE % w w = Weight of the drug in nanoparticle Weight of the polymer and drug added ×100.
  2. DL % w w = Weight of the drug in nanoparticle Weight of the polymer and drug added ×100.
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