Figure 1From: Radionuclide-labeled nanostructures for In Vivo imaging of cancer In vivo PET imaging of radiolabeled gold nanoshell structure with tumor. (a) Synthesis of radiolabeled AuNS conjugates. (b) Pharmacokinetics, expressed as the percentage of the injected dose (%ID), of 64Cu-DOTA, 64Cu-DOTA-PEG2K, and 64Cu-NS at 0, 4, 20, and 44Â h p.i. Significantly different pharmacokinetics between 64Cu-NS and the two controls are evident at 4Â h p.i. (p <0.05). (c) PET images at different time points with three different probes. (64Cu-DOTA, 64Cu-DOTA-PEG2K, and 64Cu-NS) (d) Biodistribution of 64Cu-NS in several major organs. (Adapted with permission from Ref. 18. Copyright (2010) Elsevier).Back to article page