Fig. 15
From: Nanostructured plasmonic substrates for use as SERS sensors
a–d Reproduced with permission from Ref. [67], © 2014, American Chemical Society. e, f Reproduced with permission from Ref. [90], © 2005, American Chemical Society. g, h Reproduced with permission from Ref. [91], © 2015, John Wiley and Sons
Bio-imaging and bio-sensing. a Raman spectra collected at two different positions of an ischemic murine brain in the core (red) or its contralateral region (blue). b SERS images of ischemic and control samples at 518 and 736 cm−1. c Raman spectra of eight different adenylate molecules. d SERS images of adenosine and inosine. e Schematic diagram of an AgFON substrate functionalized with a decanethiol (DT)/mercaptohexanol (MH) layer. f Raman spectra obtained as the glucose concentration in a solution was cycled between 0 and 100 mM (A–D). Raman spectra of a saturated aqueous glucose solution (E). Subtracted Raman spectrum demonstrating the adsorption/desorption of glucose from a DT/MH-AgFON substrate (F–I). g Schematic diagram showing a double-stranded DNA (dsDNA) molecule sandwiched within the junction between two AgNP@Sp (left). Extinction spectra of an AgNP@Sp suspension and AgNP@Sp with dsDNA (right). h Raman spectra of single stranded DNA (ssDNA 1), complementary ssDNA and dsDNA obtained using the AgNP@Sp substrates.