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Nano Convergence
Fig. 2 | Nano Convergence

Fig. 2

From: Multidimensional nanomaterials for the control of stem cell fate

Fig. 2

General design scheme of NanoScript. a NanoScript is consist of a single 10 nm gold nanoparticle, DNA binding domain (DBD), activation domain (AD), and nuclear localization signal (NLS). The assembly of all components mimics a natural transcription factor. b Comparison of NanoScript with a natural transcription factor. c The DBD and AD domains on NanoScript work synergistically to mimic natural transcription factors for transcriptional modulation on expression of targeted genes. d1 and d2 NanoScript shows high mono-dispersity, efficient uptake, and nuclear localization [18]

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