Fig. 11
From: Lipid-coated ZnO nanoparticles synthesis, characterization and cytotoxicity studies in cancer cell
The TEM images of the nucleus, nucleolus, cytoplasm, and the nuclear membrane morphology after being exposed to pristine ZnO NPs and lipid-coated ZnO NPs (0, 15, 120, and 150 μg/mL) for 24 h. The images in Panel (a1–g1) are enlarged from the panel (a–g). The blue arrows indicate the malformation of nuclear morphology after NPs exposure (nuclear membrane rupture). The black and white arrows indicate the chromatin condensation (electron-dense, black structure along nuclear membrane) within the nuclei. The images in panel (h–i) are simulated exposure process of NPs