Fig. 3
From: Ultrasmall iron oxide nanoparticles induced ferroptosis via Beclin1/ATG5-dependent autophagy pathway
Effect of USIONPs on the cell inhibitory rates, intracellular ROS, concentrations of iron and ferroptosis in GBM cells. a Inhibitory rates of U251 cells treated with different concentrations of USIONPs for 24, 48, and 72 h; b Inhibitory rates of C6 cells treated with different concentrations of USIONPs for 24, 48, and 72 h; c Relative ROS levels in U251 cells and C6 cells treated with different concentrations of USIONPs for 48 h; d Relative lipid ROS levels in U251 cells and C6 cells treated with different concentrations of USIONPs for 48 h; e Iron concentrations in U251 cells and C6 cells treated with different concentrations of USIONPs for 48 h. *P < 0.05, statistically significant compared with control group. #P < 0.05, statistically significant compared with 50 μg/mL USIONPs. &P < 0.05, statistically significant compared with 100 μg/mL USIONPs