Fig. 3
Photothermal properties and cell cytotoxicity of PPCu-mediated PTT. A Temperature elevation levels of PPCu in different concentrations (mg/mL) under NIR laser irradiation. B Temperature changes of different nanocapsule formulations with NIR laser irradiation. (1), (2), (3), and (4) representing H2O@PLGA + NIR, PFP@PLGA + NIR, Cu12Sb4S13@PLGA + NIR, and PPCu + NIR, respectively. C Relative cell viability of HepG2 cells treated with DMEM or different nanocapsules. (1), (2), (3), and (4) represent DMEM, PFP@PLGA, Cu12Sb4S13@PLGA and PPCu-treated cells, respectively. D Relative cell viability of HepG2 cells treated with different nanocapsule formulations under NIR laser irradiation. (1), (2), (3), (4), and (5) represent DMEM, NIR, PFP@PLGA + NIR, Cu12Sb4S13@PLGA + NIR and PPCu + NIR-treated cells, respectively. E Relative cell viability of HepG2 cells treated with different concentrations of PPCu. The x axis represents the concentration in mg/mL. Data are presented as the mean ± SD of three independent experiments. *compared with the control, p < 0.05. ** compared with the control, p < 0.01. *** compared with the control, p < 0.001