Fig. 5From: PFP@PLGA/Cu12Sb4S13-mediated PTT ablates hepatocellular carcinoma by inhibiting the RAS/MAPK/MT-CO1 signaling pathwayHyperthermia inhibits proliferation and induces apoptosis in HCC cells in vitro. A Cell viability of HepG2, HCCLM3 and Huh7 cells analyzed by MTT assays with increasing gradients of hyperthermia (43–60 °C). B Representative cell morphology images of HepG2, HCCLM3 and Huh7 cells with hyperthermia treatment. C Representative images of Calcein AM and PI costained cells by fluorescence microscope. D The expression of Bax and Bcl-2 explored by western blotting with β-actin used as a control. Data are presented as the mean ± SD of three independent experimentsBack to article page