Fig. 7

Hyperthermia inhibits HCC migration and invasion in vitro and in vivo. A Representative images of migration assays for HCC cells in different groups. B Representative images of invasion assays for HCC cells. C E-cadherin, N-cadherin, Vimentin and ZEB2 expression evaluated by western blotting in HCC cells. D Holistic view and H&E staining of excised lungs from a mouse model of metastasis. Representative images of lung tissues were shown in the left panel. Arrows indicate the location of metastatic lung foci. Corresponding H&E staining of metastatic lung foci were shown in the right panel. The scale bar = 100 μm. E Incidence of metastatic lung nodules of each group. **p < 0.01