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Table 1 Comparison of the cytotoxicity of the DE-ZnO with other ZnOs

From: Diatomaceous earth/zinc oxide micro-composite assisted antibiotics in fungal therapy

Safety dosage

Cytotoxicity (IC50)

Oral (Rat)

ZnO

 ~ 10 µg/mL [39]

5 mg/kg

SiO2

500 µg/mL [40]

SiO2-ZnO

100 μg/mL [41]

DE-ZnO (Our work)

3.0 mg/mL

300 mg/kg