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Fig. 7 | Nano Convergence

Fig. 7

From: Metal complexation-mediated stable and biocompatible nanoformulation of clinically approved near-infrared absorber for improved tumor targeting and photonic theranostics

Fig. 7

In vivo PTT in a HT-29 tumor-bearing mouse model. a Temperature changes at the tumor during treatment with laser alone or ICG-Fe NPs + laser. b Photographs of HT-29 tumor-bearing mice treated with PBS or ICG-Fe NPs + laser. c Representative axial in vivo T2-weighted MRI images of mice treated with ICG-Fe NPs + laser. d Tumor volume changes estimated via MRI for 14 days post-treatment. Laser irradiation (785 nm, 1.5 W) was performed for 10 min 24 h after intravenous injection. The yellow arrow indicates a tumor region. Data are means ± SD based on 3 mice per group. **P < 0.01; ***P < 0.001 (n = 3) using t-test

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