Fig. 8
From: Gas-stabilizing nanoparticles for ultrasound imaging and therapy of cancer
Adapted from reference [46], Copyright 2018, American Chemical Society
Ablation of tumor spheroids using HIFU and GSNs. a Schematic of the experimental setup. b Bright field and fluorescence images of a Calcein AM stained spheroid before and after HIFU treatment. c Representative bright field and fluorescence images of Calcein AM stained spheroids at different conditions: an untreated, a heat treated (dead), a HIFU treated in the absence of GSNs, and HIFU treated in the presence of nonresponsive MSNs. d Mean fluorescence intensities for spheroids treated at different conditions.