Fig. 5
From: Protein nanoparticles directed cancer imaging and therapy
Schematic illustration of the therapy and the therapeutic effect of the tumor [168]. Upper: Schematic illustration of the construction of dual antigens loaded HBc VLP and the subcutaneous inoculation; Bottom left: Results of treatment of lung metastases. Compared to saline and single antigen-loaded VLPs, hybrid VLPs significantly inhibited the lung metastasis of melanoma; Bottom right: Results of treatment of subcutaneous melanoma. Compared to saline and single antigen-loaded VLPs, hybrid VLPs inhibited tumor growth and reduced the tumor volume to the maximum extent