From: Protein nanoparticles directed cancer imaging and therapy
Preparation strategy | Advantages | Disadvantages | Key factors |
---|---|---|---|
Desolvation | Mild conditions, without surfactants, and simple process [72] | Unstable particle size [34] | pH [72] |
Emulsification | Uniform size [99] | Monodisperse droplets [99] | |
Salting out | Simple and green preparation [67] | Wide size distribution [102] | pH [102] |
Spray drying | Good particle dispersion, convenient operation and control, and suitable for mass production [104, 106] | Equipment support required [107] | Surfactant concentrations and spray mesh sizes [107] |
Self-assembly | Reversible [110] | Limited scope of application | pH [112] |