Fig. 5
From: Bioenzyme-based nanomedicines for enhanced cancer therapy
Reproduced with permission from [77]. Copyright 2019, American Chemical Society
a Illustration of the proposed mechanism for the photoactivated synergistic therapeutic action of organic semiconducting polymer pro-nanoenzyme (OSPE) including PDT and intracellular RNA degradation. b Schematic illustration of OSPE-mediated complete inhibition of tumor growth and metastasis. c The tumor growth curves in 4T1 tumor-bearing mice. d Histological hematoxylin and eosin staining of pulmonary metastatic tumors in 4T1 tumor-bearing mice. Tumors were indicated by the black dashed curves. e Quantitative analysis of pulmonary metastatic nodules in different treatment groups.