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Fig. 9 | Nano Convergence

Fig. 9

From: Recent advances in carbon quantum dots for virus detection, as well as inhibition and treatment of viral infection

Fig. 9

Copyright © 2019 WILEY‐VCH Verlag GmbH & Co. KGaA

A Representative photographs of mice on day 7 post-infection (a) without and (b) treated with Cur-CQDs-180 (25 mg kg−1). The red arrow indicates apparent limb paralysis in the untreated infected mice. B survival rates, C clinical scores, and D body weights of (i) newborn mice without infection and (ii−iv) newborn mice intraperitoneally injected with (ii) PBS, (iii) curcumin (25 mg kg−1), or (iv) Cur-CQDs-180 (25 mg kg−1) followed by intraperitoneal injection of EV71 at the dose of 2 × 106 PFU. A group of uninfected mice treated with sterile PBS was used as an uninfected control. The curcumin or Cur-CQDs-180 treatment was performed every 12 h daily for seven consecutive days. The mice were monitored for 15 d [202]. Reproduced with permission.

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