Fig. 5

Peptide assembles into β-sheets in the presence of Cu(II) and forms fibrils. A CD spectra of L9 4ʹPyA peptide with 1 equiv of Cu(II). Hydrogel samples were assembled from L9 4ʹPyA (1 wt%, 7.5 mM) with (P + Cu(II)) or without Cu(II) (P) in buffer (50 mM HEPES, pH 8), incubated overnight at 37 °C and the spectra were measured using 0.1 mm cuvette. B TEM image showing the fibrils of the hydrogel formed from F9 4ʹPyA (1 wt%) and Cu(II) (1 equiv) in buffer