Fig. 2

Schematic illustration of nanoprobe for integrating diagnosis and treatment in multidrug resistance (MDR) tumor cells, wherein, the frame displays the sequence information for the entire reaction (Panel A). The confocal fluorescence images of intracellular doxorubicin (DOX) accumulation in MCF-7/Adr cells with different treatments of Tris–HCl, T2/A3/L2-gold nanoparticles (AuNPs), T1/A4/L1/Dox-AuNPs, and T1/A3/L1/Dox-AuNPs (Panel B). The therapeutic effect of the proposed nanoprobe on MCF-7/Adr cells and L-02 cells at different time is also shown (Panel C). Reprinted with permission from Talanta,