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Fig. 2 | Nano Convergence

Fig. 2

From: Nanoscale fluorescence imaging of biological ultrastructure via molecular anchoring and physical expansion

Fig. 2

General workflow of expansion microscopy (ExM). Biological samples are first infused with a chemical anchor and polymerized in situ to form a sample-hydrogel composite. It then goes through a homogenization step, in which the molecules and structures that maintain the mechanical integrity of the sample are broken down. Finally, the sample-hydrogel composite is dialyzed in water for expansion

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