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Fig. 8 | Nano Convergence

Fig. 8

From: Nanoscale fluorescence imaging of biological ultrastructure via molecular anchoring and physical expansion

Fig. 8

(Reprinted/adapted by permission from Springer Nature: Chen et al. [59], copyright 2016)

a Single-molecule FISH (smFISH) image of XIST long non-coding RNA (lncRNA) in the nucleus of an HEK293 cell before expansion (the white line denotes the nuclear envelope). b As in a, using Expansion Fluorescence In Situ Hybridization (ExFISH). Scale bars, 2 μm (6.6 μm).

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