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Table 1 Clinical assay results for SARS-CoV-2 and influenza A virus using RT-PCR, commercial LFA, and dual-mode SERS-LFA strips performed on 39 patient samples

From: Dual-mode SERS-based lateral flow assay strips for simultaneous diagnosis of SARS-CoV-2 and influenza a virus

Sample No. Ct value (ORF1 RNA) Group LFA (P/N) Dual-mode SERS-LFA
Ratio (TL1/CL) P/N
SARS-CoV-2
Positive
P1 18.87 < 20 P 1.601 P
P2 22.78 20–25 P 0.215 P
P3 22.9 P 0.285 P
P4 23.47 P 0.54 P
P5 23.9 N 0.096 P
P6 24.59 P 0.209 P
P7 24.68 P 1.138 P
P8 24.95 P 0.107 P
P9 25.12 25–30 P 0.113 P
P10 25.83 P 0.133 P
P11 26.57 P 0.236 P
P12 26.65 P 0.123 P
P13 26.87 N 0.064 P
P14 27.34 P 0.072 P
P15 29.52 N 0.067 P
P16 29.69 P 0.292 P
P17 29.7 N 0.012 N
P18 30.07 > 30 P 0.077 P
P19 30.45 N 0.142 P
  P20 30.77 N 0.029 N
P21 31.25 N 0.042 N
P22 32.38 N 0.022 N
P23 32.83 N 0.108 P
P24 33.09 N 0.075 P
P25 33.88 N 0.018 N
P26 33.96 N 0.027 N
P27 34.85 N 0.080 P
P28 35.92 N 0.145 P
Sample No. Ct value ( M RNA) Group LFA (P/N) Dual-mode SERS-LFA
Ratio (TL2/CL) P/N
Influenza A virus
Positive
P1 25 25–30 P 0.073 P
P2 25.67 P 0.082 P
P3 25.67 P 0.335 P
P4 27.67 N 0.230 P
P5 32.67 > 30 P 0.099 P
P6 33.67 N 0.082 P
Sample No. Ct value Group LFA (P/N) Dual-mode SERS-LFA
Ratio (TL1/CL) Ratio (TL2/CL) P/N
Negative N1 N/A Negative N 0.018 0.016 N
N2 N/A N 0.029 0.027 N
N3 N/A N 0.027 0.012 N
N4 N/A N 0.022 0.017 N
N5 N/A N 0.011 0.027 N