Fig. 12
From: Functional photoacoustic imaging: from nano- and micro- to macro-scale
Label-free characterization of intrahepatic fat accumulation in liver steatosis, using near-infrared MSOT. a Clinical MSOT images with ultrasound-aided ROI delineation of subcutaneous fat (SAT) and the liver. b Preclinical MSOT imaging with cryoimaging-aided ROI selection of SAT and the liver. Comparative normalized ratio spectra, and normalized liver ROI/background mean pixel intensity ratio at 930 nm for c for the whole participant cohort (steatotic, n = 5; healthy, n = 5), and d for the whole animal model cohort (high fat diet, n = 5; regular chow diet, n = 5). The images are reproduced with permission from [173]