Fig. 19

a Schematic of the synthesis process of the nanozyme using macroporous silica nanoparticles. b UV-induced uncapping of the nanozymes due to the change in azobenzene conformation. c Bioorthogonal synthesis of mitochondria-targeting Rhodamine 110 derivative after the UV-induced activation of nanozymes. d Bright-field image of HeLa cells. e Nanozyme-catalyzed release of the fluorophore. f Cells incubated with MitoTracker® Ref CMXRos. g Merging of (e) and (f) to show the colocalization of the fluorophore and the mitochondrion. Reprinted from Ref. [196] with permission from Springer. Copyright 2018