Fig. 24

a Schematic of the synthesis process of the Cu SCNP. b Schematic of the SCNP functionalization and cross-linking with a Cu-chelating ligand. c SCNP-mediated "click" reaction that formed the fluorescent coumarin derivative. d Catalytic performance of SCNPs with different cross-linking moieties. e Schematic of the "click" reaction mechanism between propargyl-functionalized glycans in the cell surface and azide-functionalized coumarin. f Confocal images of the cell surface labeled with H460 cells after incubation with Cu-SCNP, azide-functionalized coumarin, and sodium ascorbate. Reprinted from Ref. [200] with permission from the American Chemical Society. Copyright 2019