Fig. 28
From: Biomimetic and bioorthogonal nanozymes for biomedical applications
a Nanozyme fabrication using a PONI-C11-TMA and FeTPP. b Transition electron microscopy and dynamic light scattering (DLS) characterization of nanozymes. c Schematic of the fluorophore and antimicrobial drug release in the bacterial biofilm mediated by the nanozyme. d, e Bioorthogonal release of moxifloxacin and bacteria viability of E. coli biofilm after treatment with prodrug and nanozyme demonstrates comparable efficiency to that of the free drug. f, g Bioorthogonal release of ciprofloxacin and bacteria viability of P. aeruginosa biofilm after treatment with prodrug and nanozyme demonstrates comparable efficiency to that of the free drug. Reprinted from Ref. [184] with permission from the American Chemical Society. Copyright 2020