Fig. 29
From: Biomimetic and bioorthogonal nanozymes for biomedical applications
a Structure of FeTPP. b Bioorthogonal activation of the azide-protected moxifloxacin (pro-Mox) at 37 °C. c Structure of the organic ligand attached to Au NP core. d Mechanism of the temperature-controlled activation of nanozymes. e Therapeutic efficacy of nanozymes and prodrugs at 37 and 25 °C. Nanozyme exhibited negligible bacteria-killing activity at 25 °C and activity similar to that of the free drug at 37 °C. Reprinted from Ref. [204] with permission from Elsevier Inc. Copyright 2020