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Nano Convergence
Fig. 6 | Nano Convergence

Fig. 6

From: Upconverting-photon quenching-mediated perforation influx as an intracellular delivery method using posAuNP@UCNPs nanocomposites for osteoarthritis treatment

Fig. 6

Comparison of therapeutic efficacy between UCPPin and PassT for intracellular delivery of baricitinib in an in vitro model of osteoarthritis. A Schematic diagram of the experimental procedure. B Inhibition of STAT1 and STAT3 phosphorylation by baricitinib analyzed by western blotting. C Evaluation of IL-6 levels using different intracellular delivery methods on Day 1. D Extracellular matrix (ECM) expression levels analyzed by western blotting E and immunofluorescence at Week 1 and Week 2, using different intracellular delivery methods

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