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Nano Convergence
Fig. 4 | Nano Convergence

Fig. 4

From: Effect of gut microbiota-derived metabolites and extracellular vesicles on neurodegenerative disease in a gut-brain axis chip

Fig. 4

Effect of microbe-derived metabolites on synaptic plasticity. A Representative immunofluorescent images of synaptic plasticity-related proteins. Dendrite segments (insets) are enlarged to show individual puncta. White dot lines indicate the bridge microchannels. Scale bars are 100 μm. B Analysis of GAP43 and PSD95-positive cell intensity in the brain chip after treatment with Hy2782- and Hy7714-derived metabolites. C Analysis of NeuroD1- and Nestin-positive cell intensity in the brain chip after treatment with Hy2782- and Hy7714-derived metabolites

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