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Fig. 6 | Nano Convergence

Fig. 6

From: Effect of gut microbiota-derived metabolites and extracellular vesicles on neurodegenerative disease in a gut-brain axis chip

Fig. 6

Effect of microbe-derived exosomes on synaptic plasticity. A Representative immunofluorescent images of synaptic plasticity-related proteins. Dendrite segments (insets) are enlarged to show individual puncta. White dot lines indicate the bridge microchannels. Scale bars are 100 μm. B Analysis of GAP43- and PSD95-positive cell intensity in the brain chip after treatment with Hy2782- and Hy7714-derived exosomes. C Analysis of NeuroD1- and Nestin-positive cell intensity in the brain chip after treatment with Hy2782- and Hy7714-derived exosomes

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