Table 2 Scoring parameters used to assess histological score
Score | Colonic damage | Cell infiltration (Mucosa) / (submucosa) / (serosa) |
|---|---|---|
0 | Normal | Normal |
1 | Hyperproliferation, irregular crypts, and goblet cell loss | Mild |
2 | Mild to moderate crypt loss (10–50%) | Modest |
3 | Severe crypt loss (50–90%) | Severe |
4 | Complete crypt loss, surface epithelium intact | – |
5 | Small- to medium-sized ulcers (< 10 crypt widths) | – |
6 | Large ulcers (≥ 10 crypt widths) | – |