Cell type | Advantages | Disadvantages | Ref. |
---|---|---|---|
Primary cells | Easy to obtain, closest to the body’s cells | Acquiring and isolating primary cells is a costly and time-consuming process, complicated by the heterogeneity and inter-donor variability | [122] |
Cell lines | Standardization, scale, low cost | The genome of the cell has been modified, resulting in the absence of certain traits present in the primary cell | |
iPSCs | Provides tissue specific cell types | Multiple differentiation is necessary to acquire target cells |