Organs-on-a-chip and microphysiological systems pro-vide new opportunities to create microengineered in vitro models of complex human physiological systems with unprecedented realism and predictive capacity. With the rapid evolution of this disruptive technology, increasing attention is being paid to its potential as a novel platform to enable and facilitate research in nano-science and engineering. Conversely, efforts are under-way to leverage nanoengineering techniques to advance the capabilities of organ-on-a-chip systems for a variety of biomedical applications. Motivated by these emerg-ing trends, this special issue aims to introduce recent interdisciplinary research efforts directed towards the convergence of organ-on-a-chip with nanotechnology.
Dongeun (Dan) Huh, University of Pennsylvania, USA