Y.-Q. Xie, L. Wei, L. Tang, Immunoengineering with biomaterials for enhanced cancer immunotherapy. WIREs Nanomed. Nanobiotechnol. 10(4), e1506 (2018)
Article
Google Scholar
S.Y. Neshat, S.Y. Tzeng, J.J. Green, Gene delivery for immunoengineering. Curr. Opin. Biotechnol. 66, 1–10 (2020)
Article
CAS
Google Scholar
M.S. Goldberg, Immunoengineering: how nanotechnology can enhance cancer immunotherapy. Cell 161(2), 201–204 (2015)
Article
CAS
Google Scholar
J.J. Green, Immunoengineering has arrived. J. Biomed. Mater. Res., Part A 109(4), 397–403 (2021)
Article
CAS
Google Scholar
N.-B. Hao et al., Macrophages in tumor microenvironments and the progression of tumors. Clin. Dev. Immunol 2012, 948098 (2012)
Article
CAS
Google Scholar
W. Zhang et al., Depletion of tumor-associated macrophages enhances the effect of sorafenib in metastatic liver cancer models by antimetastatic and antiangiogenic effects. Clin. Cancer Res. 16(13), 3420 (2010)
Article
CAS
Google Scholar
X. Cai et al., Re-polarization of tumor-associated macrophages to pro-inflammatory M1 macrophages by microRNA-155. J. Mol. Cell Biol. 4(5), 341–343 (2012)
Article
CAS
Google Scholar
H. Deng, Z. Zhang, The application of nanotechnology in immune checkpoint blockade for cancer treatment. J. Control. Release 290, 28–45 (2018)
Article
CAS
Google Scholar
F. Ordikhani et al., Targeting antigen-presenting cells by anti-PD-1 nanoparticles augments antitumor immunity. JCI insight 3(20), e122700 (2018)
Article
Google Scholar
N. Zhang et al., Photothermal therapy mediated by phase-transformation nanoparticles facilitates delivery of anti-PD1 antibody and synergizes with antitumor immunotherapy for melanoma. J. Control. Release 306, 15–28 (2019)
Article
CAS
Google Scholar
Z. Wang et al., Peptide vaccine-conjugated mesoporous carriers synergize with immunogenic cell death and PD-L1 blockade for amplified immunotherapy of metastatic spinal. J. Nanobiotechnol. 19(1), 243 (2021)
Article
CAS
Google Scholar
C. Wang et al., Inflammation-triggered cancer immunotherapy by programmed delivery of CpG and anti-PD1 antibody. Adv. Mater. 28(40), 8912–8920 (2016)
Article
CAS
Google Scholar
C. Wang et al., Immunological responses triggered by photothermal therapy with carbon nanotubes in combination with anti-CTLA-4 therapy to inhibit cancer metastasis. Adv. Mater. 26(48), 8154–8162 (2014)
Article
CAS
Google Scholar
J. Xu et al., Near-infrared-triggered photodynamic therapy with multitasking upconversion nanoparticles in combination with checkpoint blockade for immunotherapy of colorectal cancer. ACS Nano 11(5), 4463–4474 (2017)
Article
CAS
Google Scholar
Y. Xu et al., Sendai virus acts as a nano-booster to excite dendritic cells for enhancing the efficacy of CD47-directed immune checkpoint inhibitors against breast carcinoma. Mater. Chem. Front. 5(1), 223–237 (2021)
Article
CAS
Google Scholar
B. Hintersteiner et al., Microheterogeneity of therapeutic monoclonal antibodies is governed by changes in the surface charge of the protein. Biotechnol. J. 11(12), 1617–1627 (2016)
Article
CAS
Google Scholar
N. Shobaki et al., Manipulating the function of tumor-associated macrophages by siRNA-loaded lipid nanoparticles for cancer immunotherapy. J. Control. Release 325, 235–248 (2020)
Article
CAS
Google Scholar
S.Y. Kwak et al., PLGA nanoparticles codelivering siRNAs against programmed cell death protein-1 and its ligand gene for suppression of colon tumor growth. Mol. Pharm. 16(12), 4940–4953 (2019)
Article
CAS
Google Scholar
Y. Wu et al., Enha ncing PD-1 Gene Silence in T Lymphocytes by Comparing the Delivery Performance of Two Inorganic Nanoparticle Platforms. Nanomaterials (2019). https://doi.org/10.3390/nano9020159
Article
Google Scholar
Y. Wu et al., Silencing PD-1 and PD-L1 with nanoparticle-delivered small interfering RNA increases cytotoxicity of tumor-infiltrating lymphocytes. Nanomedicine (Lond) 14(8), 955–967 (2019)
Article
CAS
Google Scholar
J. Li et al., Biodegradable calcium phosphate nanoparticle with lipid coating for systemic siRNA delivery. J. Control. Release 142(3), 416–421 (2010)
Article
CAS
Google Scholar
Y. Chen et al., Tumor-associated macrophages: an accomplice in solid tumor progression. J. Biomed. Sci. 26(1), 78 (2019)
Article
CAS
Google Scholar
C. Werno et al., Knockout of HIF-1α in tumor-associated macrophages enhances M2 polarization and attenuates their pro-angiogenic responses. Carcinogenesis 31(10), 1863–1872 (2010)
Article
CAS
Google Scholar
S. Zhu et al., Targeting of tumor-associated macrophages made possible by PEG-sheddable mannose-modified nanoparticles. Mol. Pharm. 10(9), 3525–3530 (2013)
Article
CAS
Google Scholar
Y. Zhou et al., Anti-CD206 antibody-conjugated Fe3O4-based PLGA nanoparticles selectively promote tumor-associated macrophages to polarize to the pro-inflammatory subtype. Oncol. Lett. 20(6), 298 (2020)
Article
CAS
Google Scholar
F. Zhang et al., Genetic programming of macrophages to perform anti-tumor functions using targeted mRNA nanocarriers. Nat. Commun. 10(1), 3974 (2019)
Article
CAS
Google Scholar
M. Li et al., Optimized nanoparticle-mediated delivery of CRISPR-Cas9 system for B cell intervention. Nano Res. 11(12), 6270–6282 (2018)
Article
CAS
Google Scholar
D.N. Nguyen et al., Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency. Nat. Biotechnol. 38(1), 44–49 (2020)
Article
CAS
Google Scholar
Y.-W. Lee et al., In vivo editing of macrophages through systemic delivery of CRISPR-Cas9-ribonucleoprotein-nanoparticle nanoassemblies. Advanced therapeutics 2(10), 1900041 (2019)
Article
CAS
Google Scholar
X. Liu et al., CRISPR-Cas9-mediated multiplex gene editing in CAR-T cells. Cell Res. 27(1), 154–157 (2017)
Article
CAS
Google Scholar
J.M. Pitt et al., Dendritic cell–derived exosomes for cancer therapy. J. Clin. Investig. 126(4), 1224–1232 (2016)
Article
Google Scholar
L. Zhu et al., Exosomes derived from natural killer cells exert therapeutic effect in melanoma. Theranostics 7(10), 2732–2745 (2017)
Article
CAS
Google Scholar
H.Y. Xu et al., CD8+ T cells stimulated by exosomes derived from RenCa cells mediate specific immune responses through the FasL/Fas signaling pathway and combined with GM-CSF and IL-12, enhance the anti-renal cortical adenocarcinoma effect. Oncol. Rep 42(2), 866–879 (2019)
CAS
Google Scholar
L. Cheng, Y. Wang, L. Huang, Exosomes from M1-polarized macrophages potentiate the cancer vaccine by creating a pro-inflammatory microenvironment in the lymph node. Mol. Ther. 25(7), 1665–1675 (2017)
Article
CAS
Google Scholar
L. Li et al., IL-12 stimulates CTLs to secrete exosomes capable of activating bystander CD8+ T cells. Sci. Rep. 7(1), 13365 (2017)
Article
CAS
Google Scholar
Y. Enomoto et al., Cytokine-enhanced cytolytic activity of exosomes from NK Cells. Cancer Gene Ther (2021). https://doi.org/10.1038/s41417-021-00352-2
Article
Google Scholar
N. Seo et al., Activated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells. Nat. Commun. 9(1), 435 (2018)
Article
CAS
Google Scholar
Y.-T. Kang et al., On-chip biogenesis of circulating NK cell-derived exosomes in non-small cell lung cancer exhibits antitumoral activity. Adv. Sci. 8(6), 2003747 (2021)
Article
CAS
Google Scholar
W. Fu et al., CAR exosomes derived from effector CAR-T cells have potent antitumour effects and low toxicity. Nat. Commun. 10(1), 4355 (2019)
Article
CAS
Google Scholar
P. Yang et al., The exosomes derived from CAR-T cell efficiently target mesothelin and reduce triple-negative breast cancer growth. Cell. Immunol. 360, 104262 (2021)
Article
CAS
Google Scholar
G.R. Willis, S. Kourembanas, S.A. Mitsialis, Toward exosome-based therapeutics: isolation, heterogeneity, and fit-for-purpose potency. Front. Cardiovasc. Med. (2017). https://doi.org/10.3389/fcvm.2017.00063
Article
Google Scholar
J. Chen et al., In situ cancer vaccination using lipidoid nanoparticles. Sci. Adv. (2021). https://doi.org/10.1126/sciadv.abf1244
Article
Google Scholar
J. Liu et al., Nanoparticle cancer vaccines: design considerations and recent advances. Asian J. Pharm. Sci. 15(5), 576–590 (2020)
Article
Google Scholar
M. Hirayama, Y. Nishimura, The present status and future prospects of peptide-based cancer vaccines. Int. Immunol. 28(7), 319–328 (2016)
Article
CAS
Google Scholar
D.W. Crews, J.A. Dombroski, M.R. King, Prophylactic cancer vaccines engineered to elicit specific adaptive immune response. Front. Oncol. 11, 626463–626463 (2021)
Article
Google Scholar
S.J. Tsai, A. Amerman, C.M. Jewell, Altering antigen charge to control self-assembly and processing of immune signals during cancer vaccination. Front. Immunol. (2021). https://doi.org/10.3389/fimmu.2020.613830
Article
Google Scholar
Z. Xu et al., Multifunctional nanoparticles co-delivering Trp2 peptide and CpG adjuvant induce potent cytotoxic T-lymphocyte response against melanoma and its lung metastasis. J. Control. Release 172(1), 259–265 (2013)
Article
CAS
Google Scholar
J. Heuts et al., Cationic nanoparticle-based cancer vaccines. Pharmaceutics 13(5), 596 (2021)
Article
CAS
Google Scholar
H. Kim, T.S. Griffith, J. Panyam, Poly(d, l-lactide-co-glycolide) nanoparticles as delivery platforms for TLR7/8 agonist-based cancer vaccine. J. Pharmacol. Exp. Ther. 370(3), 715–724 (2019)
Article
CAS
Google Scholar
F.E. González et al., Tumor cell lysates as immunogenic sources for cancer vaccine design. Hum. Vaccin. Immunother. 10(11), 3261–3269 (2014)
Article
Google Scholar
Y.-Z. Gu, X. Zhao, X.-R. Song, Ex vivo pulsed dendritic cell vaccination against cancer. Acta Pharmacol. Sin. 41(7), 959–969 (2020)
Article
CAS
Google Scholar
C.J.E. Wahlund et al., Exosomes from antigen-pulsed dendritic cells induce stronger antigen-specific immune responses than microvesicles in vivo. Sci. Rep. 7(1), 17095 (2017)
Article
CAS
Google Scholar
A.J. Stephens, N.A. Burgess-Brown, S. Jiang, Beyond just peptide antigens: the complex world of peptide-based cancer vaccines. Front. Immunol. (2021). https://doi.org/10.3389/fimmu.2021.696791
Article
Google Scholar
M.A. Liu, DNA vaccines: an historical perspective and view to the future. Immunol. Rev. 239(1), 62–84 (2011)
Article
CAS
Google Scholar
M.V. Stegantseva et al., Multi-antigen DNA vaccine delivered by polyethylenimine and Salmonella enterica in neuroblastoma mouse model. Cancer Immunol. Immunother. 69(12), 2613–2622 (2020)
Article
CAS
Google Scholar
B.J. Ledwith et al., Plasmid DNA vaccines: investigation of integration into host cellular DNA following intramuscular injection in mice. Intervirology 43(4–6), 258–272 (2000)
Article
CAS
Google Scholar
B. Yang et al., DNA vaccine for cancer immunotherapy. Hum. Vaccin. Immunother. 10(11), 3153–3164 (2014)
Article
Google Scholar
G. Minigo et al., Poly-l-lysine-coated nanoparticles: A potent delivery system to enhance DNA vaccine efficacy. Vaccine 25(7), 1316–1327 (2007)
Article
CAS
Google Scholar
M.A. Liu, A Comparison of Plasmid DNA and mRNA as Vaccine Technologies. Vaccines 7(2), 37 (2019)
Article
CAS
Google Scholar
Z. Liu et al., Alginic acid-coated chitosan nanoparticles loaded with legumain DNA vaccine: effect against breast cancer in mice. PLoS ONE 8(4), e60190 (2013)
Article
CAS
Google Scholar
A.N. Meleshko et al., Phase I clinical trial of idiotypic DNA vaccine administered as a complex with polyethylenimine to patients with B-cell lymphoma. Hum. Vaccin. Immunother. 13(6), 1–6 (2017)
Article
CAS
Google Scholar
Y.-F. Ma, Y.-W. Yang, Delivery of DNA-based cancer vaccine with polyethylenimine. Eur. J. Pharm. Sci. 40(2), 75–83 (2010)
Article
CAS
Google Scholar
P.C. DeMuth et al., Polymer multilayer tattooing for enhanced DNA vaccination. Nat. Mater. 12(4), 367–376 (2013)
Article
CAS
Google Scholar
K. Roy et al., Oral gene delivery with chitosan–DNA nanoparticles generates immunologic protection in a murine model of peanut allergy. Nat Med 5(4), 387–391 (1999)
Article
CAS
Google Scholar
A. Vila et al., Low molecular weight chitosan nanoparticles as new carriers for nasal vaccine delivery in mice. Eur J Pharm Biopharm 57(1), 123–131 (2004)
Article
CAS
Google Scholar
B. Sun et al., Mannose-functionalized biodegradable nanoparticles efficiently deliver DNA vaccine and promote anti-tumor immunity. ACS Appl. Mater. Interfaces. 13(12), 14015–14027 (2021)
Article
CAS
Google Scholar
R. Deng et al., Revisit the complexation of PEI and DNA—how to make low cytotoxic and highly efficient PEI gene transfection non-viral vectors with a controllable chain length and structure? J. Control. Release 140(1), 40–46 (2009)
Article
CAS
Google Scholar
Z.U. Rehman, D. Hoekstra, I.S. Zuhorn, Mechanism of polyplex- and lipoplex-mediated delivery of nucleic acids: real-time visualization of transient membrane destabilization without endosomal lysis. ACS Nano 7(5), 3767–3777 (2013)
Article
CAS
Google Scholar
D. Liu et al., STING directly activates autophagy to tune the innate immune response. Cell Death Differ. 26(9), 1735–1749 (2019)
Article
CAS
Google Scholar
Y. Fu et al., Inhibition of cGAS-mediated interferon response facilitates transgene expression. IScience 23(4), 101026 (2020)
Article
CAS
Google Scholar
R. Ni, R. Feng, Y. Chau, Synthetic approaches for nucleic acid delivery: choosing the right carriers. Life (Basel) 9(3), 59 (2019)
CAS
Google Scholar
Y. Hu et al., A highly efficient synthetic vector: nonhydrodynamic delivery of DNA to hepatocyte nuclei in vivo. ACS Nano 7(6), 5376–5384 (2013)
Article
CAS
Google Scholar
K.J. Hassett et al., Optimization of lipid nanoparticles for intramuscular administration of mRNA vaccines. Mol. Ther. Nucleic Acids 15, 1–11 (2019)
Article
CAS
Google Scholar
S.S. Nogueira et al., Polysarcosine-functionalized lipid nanoparticles for therapeutic mRNA delivery. ACS Appl. Nano Mater. 3(11), 10634–10645 (2020)
Article
CAS
Google Scholar
S. Sabnis et al., A novel amino lipid series for mRNA delivery: improved endosomal escape and sustained pharmacology and safety in non-human primates. Mol. Ther. 26(6), 1509–1519 (2018)
Article
CAS
Google Scholar
M. Yanez Arteta et al., Successful reprogramming of cellular protein production through mRNA delivered by functionalized lipid nanoparticles. Proc. Natl. Acad. Sci. 115(15), E3351 (2018)
Article
CAS
Google Scholar
S. Wilhelm et al., Analysis of nanoparticle delivery to tumours. Nat. Rev. Mater. 1(5), 16014 (2016)
Article
CAS
Google Scholar
L. Tang et al., Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery. Nat. Biotechnol. 36(8), 707–716 (2018)
Article
CAS
Google Scholar
M.T. Stephan et al., Therapeutic cell engineering with surface-conjugated synthetic nanoparticles. Nat. Med. 16(9), 1035–1041 (2010)
Article
CAS
Google Scholar
M.T. Stephan et al., Synapse-directed delivery of immunomodulators using T-cell-conjugated nanoparticles. Biomaterials 33(23), 5776–5787 (2012)
Article
CAS
Google Scholar
Y. Zheng et al., Enhancing Adoptive Cell Therapy of Cancer through Targeted Delivery of Small-Molecule Immunomodulators to Internalizing or Noninternalizing Receptors. ACS Nano 11(3), 3089–3100 (2017)
Article
CAS
Google Scholar
Y.-Q. Xie et al., Redox-responsive interleukin-2 nanogel specifically and safely promotes the proliferation and memory precursor differentiation of tumor-reactive T-cells. Biomaterials Science 7(4), 1345–1357 (2019)
Article
CAS
Google Scholar
B. Huang et al., Active targeting of chemotherapy to disseminated tumors using nanoparticle-carrying T cells. Sci. Transl. Med. (2015). https://doi.org/10.1126/scitranslmed.aaa5447
Article
Google Scholar
R.B. Jones et al., Antigen recognition-triggered drug delivery mediated by nanocapsule-functionalized cytotoxic T-cells. Biomaterials 117, 44–53 (2017)
Article
CAS
Google Scholar
N. Siriwon et al., CAR-T cells surface-engineered with drug-encapsulated nanoparticles can ameliorate intratumoral T-cell hypofunction. Cancer Immunol. Res. 6(7), 812 (2018)
Article
CAS
Google Scholar
S. Chandrasekaran et al., Super natural killer cells that target metastases in the tumor draining lymph nodes. Biomaterials 77, 66–76 (2016)
Article
CAS
Google Scholar
C. Loftus et al., Activation of Human Natural Killer Cells by Graphene Oxide-Templated Antibody Nanoclusters. Nano Lett. 18(5), 3282–3289 (2018)
Article
CAS
Google Scholar
E.L. Siegler et al., Combination cancer therapy using chimeric antigen receptor-engineered natural killer cells as drug carriers. Mol. Ther 25(12), 2607–2619 (2017)
Article
CAS
Google Scholar
M.J. Mitchell et al., TRAIL-coated leukocytes that kill cancer cells in the circulation. Proc Natl Acad Sci U S A 111(3), 930–935 (2014)
Article
CAS
Google Scholar
J.J. Moon et al., Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses. Nat. Mater. 10(3), 243–251 (2011)
Article
CAS
Google Scholar
K.-I. Joo et al., Crosslinked multilamellar liposomes for controlled delivery of anticancer drugs. Biomaterials 34(12), 3098–3109 (2013)
Article
CAS
Google Scholar
H. Yin et al., Non-viral vectors for gene-based therapy. Nat. Rev. Genet. 15(8), 541–555 (2014)
Article
CAS
Google Scholar
C. Baum et al., Mutagenesis and oncogenesis by chromosomal insertion of gene transfer vectors. Hum. Gene Ther. 17(3), 253–263 (2006)
Article
CAS
Google Scholar
N. Bessis, F.J. GarciaCozar, M.C. Boissier, Immune responses to gene therapy vectors: influence on vector function and effector mechanisms. Gene Ther. 11(1), S10–S17 (2004)
Article
CAS
Google Scholar
C.E. Thomas, A. Ehrhardt, M.A. Kay, Progress and problems with the use of viral vectors for gene therapy. Nat. Rev. Genet. 4(5), 346–358 (2003)
Article
CAS
Google Scholar
D.W. Pack et al., Design and development of polymers for gene delivery. Nat. Rev. Drug Discovery 4(7), 581–593 (2005)
Article
CAS
Google Scholar
M.A. Mintzer, E.E. Simanek, Nonviral vectors for gene delivery. Chem. Rev. 109(2), 259–302 (2009)
Article
CAS
Google Scholar
T.T. Smith et al., In situ programming of leukaemia-specific T cells using synthetic DNA nanocarriers. Nat. Nanotechnol. 12(8), 813–820 (2017)
Article
CAS
Google Scholar
N.N. Parayath et al., In vitro-transcribed antigen receptor mRNA nanocarriers for transient expression in circulating T cells in vivo. Nat. Commun. 11(1), 6080 (2020)
Article
CAS
Google Scholar
P. Fonte, S. Reis, B. Sarmento, Facts and evidences on the lyophilization of polymeric nanoparticles for drug delivery. J. Control. Release 225, 75–86 (2016)
Article
CAS
Google Scholar
B.R. Olden et al., Cationic polymers for non-viral gene delivery to human T cells. J. Control. Release 282, 140–147 (2018)
Article
CAS
Google Scholar
F. Richter et al., Improved gene delivery to K-562 leukemia cells by lipoic acid modified block copolymer micelles. J. Nanobiotechnol. 19(1), 70 (2021)
Article
CAS
Google Scholar
V.S.S.A. Ayyadevara, K.-H. Roh, Calcium enhances polyplex-mediated transfection efficiency of plasmid DNA in Jurkat cells. Drug Delivery 27(1), 805–815 (2020)
Article
CAS
Google Scholar
O.B. Suhr et al., Efficacy and safety of patisiran for familial amyloidotic polyneuropathy: a phase II multi-dose study. Orphanet. J. Rare Dis. 10, 109 (2015)
Article
Google Scholar
H.C. Sum, S. Wettig, A.R. Slavcev, Impact of DNA vector topology on non-viral gene therapeutic safety and efficacy. Curr. Gene Ther. 14(4), 309–329 (2014)
Article
CAS
Google Scholar
S. Ramishetti et al., A combinatorial library of lipid nanoparticles for RNA delivery to leukocytes. Adv. Mater. 32(12), 1906128 (2020)
Article
CAS
Google Scholar
P.P.G. Guimaraes et al., Ionizable lipid nanoparticles encapsulating barcoded mRNA for accelerated in vivo delivery screening. J. Control. Release 316, 404–417 (2019)
Article
CAS
Google Scholar
M. Kim et al., Engineered ionizable lipid nanoparticles for targeted delivery of RNA therapeutics into different types of cells in the liver. Sci. Adv. (2021). https://doi.org/10.1126/sciadv.abf4398
Article
Google Scholar
M.M. Billingsley et al., Ionizable lipid nanoparticle-mediated mRNA delivery for human CAR T cell engineering. Nano Lett. 20(3), 1578–1589 (2020)
Article
CAS
Google Scholar
M.M. Billingsley et al., Orthogonal design of experiments for optimization of lipid nanoparticles for mRNA engineering of CAR T cells. Nano Lett. 22(1), 533–542 (2022)
Article
CAS
Google Scholar
K.-S. Kim et al., Multifunctional nanoparticles for genetic engineering and bioimaging of natural killer (NK) cell therapeutics. Biomaterials 221, 119418 (2019)
Article
CAS
Google Scholar
J. Wang et al., Purinergic targeting enhances immunotherapy of CD73+ solid tumors with piggyBac-engineered chimeric antigen receptor natural killer cells. J. Immunother. Cancer 6(1), 136 (2018)
Article
Google Scholar
M. Klichinsky et al., Human chimeric antigen receptor macrophages for cancer immunotherapy. Nat. Biotechnol. 38(8), 947–953 (2020)
Article
CAS
Google Scholar
L. Zhang et al., Pluripotent stem cell-derived CAR-macrophage cells with antigen-dependent anti-cancer cell functions. J. Hematol. Oncol. 13(1), 153 (2020)
Article
CAS
Google Scholar
M. Kang et al., Nanocomplex-Mediated In Vivo Programming to Chimeric Antigen Receptor-M1 Macrophages for Cancer Therapy. Adv. Mater. 33(43), 2103258 (2021)
Article
CAS
Google Scholar
C.-Y. Wu et al., Remote control of therapeutic T cells through a small molecule-gated chimeric receptor. Science 350(6258), aab4077 (2015)
Article
CAS
Google Scholar
J.H. Cho, J.J. Collins, W.W. Wong, Universal chimeric antigen receptors for multiplexed and logical control of T cell responses. Cell 173(6), 1426-1438.e11 (2018)
Article
CAS
Google Scholar
M. Jan et al., Reversible ON- and OFF-switch chimeric antigen receptors controlled by lenalidomide. Sci. Transl. Med. 13(575), eabb6295 (2021)
Article
CAS
Google Scholar
N.T. Nguyen et al., Nano-optogenetic engineering of CAR T cells for precision immunotherapy with enhanced safety. Nat. Nanotechnol. 16(12), 1424–1434 (2021)
Article
CAS
Google Scholar
I.C. Miller et al., Enhanced intratumoural activity of CAR T cells engineered to produce immunomodulators under photothermal control. Nat. Biomed. Eng. 5(11), 1348–1359 (2021)
Article
CAS
Google Scholar
K. Ahrar et al., Preclinical assessment of a 980-nm diode laser ablation system in a large animal tumor model. JVIR 21(4), 555–561 (2010)
Article
Google Scholar
O. Bozkulak et al., The 980-nm diode laser for brain surgery: histopathology and recovery period. Lasers Med. Sci. 19(1), 41–47 (2004)
Article
Google Scholar
W. Nie et al., Magnetic nanoclusters armed with responsive PD-1 antibody synergistically improved adoptive T-cell therapy for solid tumors. ACS Nano 13(2), 1469–1478 (2019)
Article
CAS
Google Scholar
S. Depil et al., ‘Off-the-shelf’ allogeneic CAR T cells: development and challenges. Nat. Rev. Drug Discov. 19(3), 185–199 (2020)
Article
CAS
Google Scholar
R.B. Belshe et al., Live attenuated versus inactivated influenza vaccine in infants and young children. N. Engl. J. Med. 356(7), 685–696 (2007)
Article
CAS
Google Scholar
P.D. Minor, Live attenuated vaccines: historical successes and current challenges. Virology 479–480, 379–392 (2015)
Article
CAS
Google Scholar
R.K. Chandra, Reduced secretory antibody response to live attenuated measles and poliovirus vaccines in malnourished children. BMJ 2(5971), 583–585 (1975)
Article
CAS
Google Scholar
M. Levine et al., Large-scale field trial of TY21A live oral typhoid vaccine in enteric-coated capsule formulation. Lancet 329(8541), 1049–1052 (1987)
Article
Google Scholar
D. Greco et al., A controlled trial of two acellular vaccines and one whole-cell vaccine against pertussis. N. Engl. J. Med. 334(6), 341–349 (1996)
Article
CAS
Google Scholar
S. Plotkin, History of vaccination. Proc. Natl. Acad. Sci. 111(34), 12283 (2014)
Article
CAS
Google Scholar
M.L. Immordino, F. Dosio, L. Cattel, Stealth liposomes: review of the basic science, rationale, and clinical applications, existing and potential. Int. J. Nanomed. 1(3), 297–315 (2006)
CAS
Google Scholar
A.K. Giddam et al., Liposome-based delivery system for vaccine candidates: Constructing an effective formulation. Nanomedicine (Lond.) 7, 1877–1893 (2012)
Article
CAS
Google Scholar
G.R. Diogo et al., Immunization with mycobacterium tuberculosis antigens encapsulated in phosphatidylserine liposomes improves protection afforded by BCG. Front. Immunol. (2019). https://doi.org/10.3389/fimmu.2019.01349
Article
Google Scholar
S.A. Khader et al., IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nat. Immunol. 8(4), 369–377 (2007)
Article
CAS
Google Scholar
D. Straßburger et al., Mannose-decorated multicomponent supramolecular polymers trigger effective uptake into antigen-presenting cells. ChemBioChem 19(9), 912–916 (2018)
Article
CAS
Google Scholar
C. Song, Y.-W. Noh, Y.T. Lim, Polymer nanoparticles for cross-presentation of exogenous antigens and enhanced cytotoxic T-lymphocyte immune response. Int. J. Nanomed. 11, 3753 (2016)
Article
CAS
Google Scholar
P. Tao et al., A bacteriophage T4 nanoparticle-based dual vaccine against anthrax and plague. MBio (2018). https://doi.org/10.1128/mBio.01926-18
Article
Google Scholar
S.A. Staroverov et al., Immunostimulatory effect of gold nanoparticles conjugated with transmissible gastroenteritis virus. Bull. Exp. Biol. Med. 151(4), 436–439 (2011)
Article
CAS
Google Scholar
A.E. Gregory et al., Conjugation of Y. pestis F1-antigen to gold nanoparticles improves immunogenicity. Vaccine 30(48), 6777–6782 (2012)
Article
CAS
Google Scholar
Y.-T. Wang et al., The use of a gold nanoparticle-based adjuvant to improve the therapeutic efficacy of hNgR-Fc protein immunization in spinal cord-injured rats. Biomaterials 32(31), 7988–7998 (2011)
Article
CAS
Google Scholar
F. Dakterzada et al., Induction of humoral immune response against Pseudomonas aeruginosa flagellin(1–161) using gold nanoparticles as an adjuvant. Vaccine 34(12), 1472–1479 (2016)
Article
CAS
Google Scholar
G. Barhate et al., Enhanced mucosal immune responses against tetanus toxoid using novel delivery system comprised of chitosan-functionalized gold nanoparticles and botanical adjuvant: characterization, immunogenicity, and stability assessment. J. Pharm. Sci. 103(11), 3448–3456 (2014)
Article
CAS
Google Scholar
E. Rodriguez-Del Rio et al., A gold glyco-nanoparticle carrying a listeriolysin O peptide and formulated with Advax™ delta inulin adjuvant induces robust T-cell protection against listeria infection. Vaccine 33(12), 1465–1473 (2015)
Article
CAS
Google Scholar
N.A. Lind et al., Regulation of the nucleic acid-sensing Toll-like receptors. Nat. Rev. Immunol. (2021). https://doi.org/10.1038/s41577-021-00577-0
Article
Google Scholar
A. De Beuckelaer et al., Type I interferons interfere with the capacity of mRNA lipoplex vaccines to elicit cytolytic T cell responses. Mol. Ther. 24(11), 2012–2020 (2016)
Article
CAS
Google Scholar
U. Sahin, K. Karikó, Ö. Türeci, mRNA-based therapeutics—developing a new class of drugs. Nat. Rev. Drug Discov. 13(10), 759–780 (2014)
Article
CAS
Google Scholar
K. Niikura et al., Gold nanoparticles as a vaccine platform: influence of size and shape on immunological responses in vitro and in vivo. ACS Nano 7(5), 3926–3938 (2013)
Article
CAS
Google Scholar
W. Tao et al., Consensus M2e peptide conjugated to gold nanoparticles confers protection against H1N1, H3N2 and H5N1 influenza A viruses. Antiviral Res. 141, 62–72 (2017)
Article
CAS
Google Scholar
R.P. Ringe et al., Neutralizing antibody induction by HIV-1 envelope glycoprotein SOSIP trimers on iron oxide nanoparticles may be impaired by mannose binding lectin. J. Virol. 94(6), e01883-e1919 (2020)
Article
CAS
Google Scholar
D. Mahony et al., In vivo delivery of bovine viral diahorrea virus, E2 protein using hollow mesoporous silica nanoparticles. Nanoscale 6(12), 6617–6626 (2014)
Article
CAS
Google Scholar
S. Dhakal et al., Mucosal immunity and protective efficacy of intranasal inactivated influenza vaccine is improved by chitosan nanoparticle delivery in pigs. Front. Immunol. (2018). https://doi.org/10.3389/fimmu.2018.00934
Article
Google Scholar
S. Dhakal et al., Biodegradable nanoparticle delivery of inactivated swine influenza virus vaccine provides heterologous cell-mediated immune response in pigs. J. Control. Release 247, 194–205 (2017)
Article
CAS
Google Scholar
C. Thomas et al., Aerosolized PLA and PLGA nanoparticles enhance humoral, mucosal and cytokine responses to hepatitis B vaccine. Mol. Pharm. 8(2), 405–415 (2011)
Article
CAS
Google Scholar
C. Jia et al., A novel human papillomavirus 16 L1 pentamer-loaded hybrid particles vaccine system: influence of size on immune responses. ACS Appl. Mater. Interfaces. 10(42), 35745–35759 (2018)
Article
CAS
Google Scholar
J. Jia et al., Adjuvanticity regulation by biodegradable polymeric nano/microparticle size. Mol. Pharm. 14(1), 14–22 (2017)
Article
CAS
Google Scholar
T. Tokatlian et al., Enhancing humoral responses against HIV envelope trimers via nanoparticle delivery with stabilized synthetic liposomes. Sci. Rep. 8(1), 16527 (2018)
Article
CAS
Google Scholar
M.C. Hanson et al., Liposomal vaccines incorporating molecular adjuvants and intrastructural T-cell help promote the immunogenicity of HIV membrane-proximal external region peptides. Vaccine 33(7), 861–868 (2015)
Article
CAS
Google Scholar
K.J. Hassett et al., Development of a highly thermostable, adjuvanted human papillomavirus vaccine. Eur. J. Pharm. Biopharm. 94, 220–228 (2015)
Article
CAS
Google Scholar
I.S. Georgiev et al., Two-component ferritin nanoparticles for multimerization of diverse trimeric antigens. ACS Infect. Dis. 4(5), 788–796 (2018)
Article
CAS
Google Scholar
S. Xu et al., mRNA vaccine era—mechanisms drug platform and clinical prospection. IJMS (2020). https://doi.org/10.3390/ijms21186582
Article
Google Scholar
S. Pascolo, Synthetic messenger RNA-based vaccines: from scorn to hype. Viruses 13(2), 270 (2021)
Article
CAS
Google Scholar
K. Leppek, R. Das, M. Barna, Functional 5′ UTR mRNA structures in eukaryotic translation regulation and how to find them. Nat. Rev. Mol. Cell Biol. 19(3), 158–174 (2018)
Article
CAS
Google Scholar
A.G. von OrlandiniNiessen et al., Improving mRNA-based therapeutic gene delivery by expression-augmenting 3′ UTRs identified by cellular library screening. Mol. Ther. 27(4), 824–836 (2019)
Article
CAS
Google Scholar
R.A. Wesselhoeft et al., RNA circularization diminishes immunogenicity and can extend translation duration in vivo. Mol. Cell 74(3), 508-520.e4 (2019)
Article
CAS
Google Scholar
L. Yang et al., COVID-19: immunopathogenesis and Immunotherapeutics. Signal Transduct. Target. Ther. 5(1), 128 (2020)
Article
CAS
Google Scholar
K.A. Dowd et al., Rapid development of a DNA vaccine for Zika virus. Science 354(6309), 237–240 (2016)
Article
CAS
Google Scholar
N. Pardi et al., mRNA vaccines—a new era in vaccinology. Nat. Rev. Drug Discovery 17(4), 261–279 (2018)
Article
CAS
Google Scholar
J. Nelson et al., Impact of mRNA chemistry and manufacturing process on innate immune activation. Sci. Adv. (2020). https://doi.org/10.1126/sciadv.aaz6893
Article
Google Scholar
K.S. Corbett et al., SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness. Nature 586(7830), 567–571 (2020)
Article
CAS
Google Scholar
L. Schoenmaker et al., mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability. Int. J. Pharm 601, 120586 (2021)
Article
CAS
Google Scholar
M.D. Buschmann et al., Nanomaterial delivery systems for mRNA vaccines. Vaccines 9(1), 65 (2021)
Article
CAS
Google Scholar
A.B. Vogel et al., BNT162b vaccines protect rhesus macaques from SARS-CoV-2. Nature 592(7853), 283–289 (2021)
Article
CAS
Google Scholar
U. Elia et al., Lipid nanoparticle RBD-hFc mRNA vaccine protects hACE2 transgenic mice against a lethal SARS-CoV-2 infection. Nano Lett. 21(11), 4774–4779 (2021)
Article
CAS
Google Scholar
M.A. Oberli et al., Lipid nanoparticle assisted mRNA delivery for potent cancer immunotherapy. Nano Lett. 17(3), 1326–1335 (2017)
Article
CAS
Google Scholar
M. Gharagozloo, S. Majewski, M. Foldvari, Therapeutic applications of nanomedicine in autoimmune diseases: from immunosuppression to tolerance induction. Nanomedicine 11(4), 1003–1018 (2015)
Article
CAS
Google Scholar
G. Nygaard, G.S. Firestein, Restoring synovial homeostasis in rheumatoid arthritis by targeting fibroblast-like synoviocytes. Nat. Rev. Rheumatol. 16(6), 316–333 (2020)
Article
Google Scholar
Z. Wen, C. Fiocchi, Inflammatory bowel disease: autoimmune or immune-mediated pathogenesis? Clin. Dev. Immunol. 11, 839572 (2004)
Article
Google Scholar
F. Chu et al., The roles of macrophages and microglia in multiple sclerosis and experimental autoimmune encephalomyelitis. J. Neuroimmunol. 318, 1–7 (2018)
Article
CAS
Google Scholar
R. Kato et al., CD4+CD25+LAG3+ T cells with a feature of Th17 cells associated with systemic lupus erythematosus disease activity. Front. Immunol. (2019). https://doi.org/10.3389/fimmu.2019.01619
Article
Google Scholar
E.M. Elli et al., Mechanisms underlying the anti-inflammatory and immunosuppressive activity of ruxolitinib. Front. Oncol. (2019). https://doi.org/10.3389/fonc.2019.01186
Article
Google Scholar
J.C.A. Broen, J.M. van Laar, Mycophenolate mofetil, azathioprine and tacrolimus: mechanisms in rheumatology. Nat. Rev. Rheumatol. 16(3), 167–178 (2020)
Article
CAS
Google Scholar
M. Naesens, D.R.J. Kuypers, M. Sarwal, Calcineurin inhibitor nephrotoxicity. Clin. J. Am. Soc. Nephrol. 4(2), 481 (2009)
Article
CAS
Google Scholar
L.J. Scott, Tocilizumab: a review in rheumatoid arthritis. Drugs 77(17), 1865–1879 (2017)
Article
CAS
Google Scholar
M. Sospedra, R. Martin, Immunology of multiple sclerosis. Annu. Rev. Immunol. 23(1), 683–747 (2004)
Article
CAS
Google Scholar
B. Hemmer et al., Immunopathogenesis and immunotherapy of multiple sclerosis. Nat. Clin. Pract. Neurol. 2, 201–211 (2006)
Article
CAS
Google Scholar
A.P. Kallaur et al., Immune-inflammatory and oxidative and nitrosative stress biomarkers of depression symptoms in subjects with multiple sclerosis: increased peripheral inflammation but less acute neuroinflammation. Mol. Neurobiol. 53(8), 5191–5202 (2016)
Article
CAS
Google Scholar
K. Kucharz et al., Post-capillary venules are the key locus for transcytosis-mediated brain delivery of therapeutic nanoparticles. Nat. Commun. 12(1), 4121 (2021)
Article
CAS
Google Scholar
D.G. Gadhave, C.R. Kokare, Nanostructured lipid carriers engineered for intranasal delivery of teriflunomide in multiple sclerosis: optimization and in vivo studies. Drug Dev. Ind. Pharm. 45(5), 839–851 (2019)
Article
CAS
Google Scholar
C. Warnke, O. Stuve, B.C. Kieseier, Teriflunomide for the treatment of multiple sclerosis. Clin Neurol Neurosurg 115(Suppl 1), S90–S94 (2013)
Article
Google Scholar
P. Kumar et al., Oral delivery of methylthioadenosine to the brain employing solid lipid nanoparticles: pharmacokinetic, behavioral, and histopathological evidences. AAPS PharmSciTech (2019). https://doi.org/10.1208/s12249-019-1296-0
Article
Google Scholar
P. Kumar et al., Preclinical explorative assessment of dimethyl fumarate-based biocompatible nanolipoidal carriers for the management of multiple sclerosis. ACS Chem. Neurosci. 9(5), 1152–1158 (2018)
Article
CAS
Google Scholar
M.P.M. van der Linden et al., Long-term impact of delay in assessment of patients with early arthritis. Arthritis Rheum. 62(12), 3537–3546 (2010)
Article
Google Scholar
N.J. Wilson et al., Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat Immunol 8(9), 950–957 (2007)
Article
CAS
Google Scholar
T. Korn et al., IL-21 initiates an alternative pathway to induce proinflammatory TH17 cells. Nature 448(7152), 484–487 (2007)
Article
CAS
Google Scholar
E. Lubberts, The IL-23–IL-17 axis in inflammatory arthritis. Nat. Rev. Rheumatol. 11(7), 415–429 (2015)
Article
CAS
Google Scholar
C. Ospelt et al., Overexpression of toll-like receptors 3 and 4 in synovial tissue from patients with early rheumatoid arthritis: Toll-like receptor expression in early and longstanding arthritis. Arthritis Rheum. 58(12), 3684–3692 (2008)
Article
CAS
Google Scholar
R. Seibl et al., Expression and regulation of toll-like receptor 2 in rheumatoid arthritis synovium. Am. J. Pathol. 162(4), 1221–1227 (2003)
Article
CAS
Google Scholar
D.A. Fox et al., Cell-cell interactions in rheumatoid arthritis synovium. Rheum. Dis. Clin. North Am. 36(2), 311–323 (2010)
Article
Google Scholar
R.R. Meka et al., IL-27-induced modulation of autoimmunity and its therapeutic potential. Autoimmun. Rev. 14(12), 1131–1141 (2015)
Article
CAS
Google Scholar
R.R. Meka, S.H. Venkatesha, K.D. Moudgil, Peptide-directed liposomal delivery improves the therapeutic index of an immunomodulatory cytokine in controlling autoimmune arthritis. J. Control. Release 286, 279–288 (2018)
Article
CAS
Google Scholar
N. Nakashima-Matsushita et al., Selective expression of folate receptor beta and its possible role in methotrexate transport in synovial macrophages from patients with rheumatoid arthritis. Arthritis Rheum. 42(8), 1609–1616 (1999)
Article
CAS
Google Scholar
E. Nogueira et al., Enhancing methotrexate tolerance with folate tagged liposomes in arthritic mice. J. Biomed. Nanotechnol. (2015). https://doi.org/10.1166/jbn.2015.2170
Article
Google Scholar
E. Nogueira et al., Neutral PEGylated liposomal formulation for efficient folate-mediated delivery of MCL1 siRNA to activated macrophages. Colloids Surf. B 155, 459–465 (2017)
Article
CAS
Google Scholar
J. Larouche et al., Immune regulation of skin wound healing: mechanisms and novel therapeutic targets. Adv. Wound Care 7(7), 209–231 (2018)
Article
Google Scholar
M. Sun et al., Rebamipide-loaded chitosan nanoparticles accelerate prostatic wound healing by inhibiting M1 macrophage-mediated inflammation via the NF-κB signaling pathway. Biomater. Sci. 8(3), 912–925 (2020)
Article
CAS
Google Scholar
O.E. Kaymakcalan et al., Antigen-mediated, macrophage-stimulated, accelerated wound healing using α-gal nanoparticles. Ann Plast Surg 80(4 Suppl 4), S196-s203 (2018)
Article
CAS
Google Scholar
J. Gan et al., Accelerated wound healing in diabetes by reprogramming the macrophages with particle-induced clustering of the mannose receptors. Biomaterials 219, 119340 (2019)
Article
CAS
Google Scholar
C. Ohnmacht et al., Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity. J. Exp. Med. 206(3), 549–559 (2009)
Article
CAS
Google Scholar
C.A. Iberg, A. Jones, D. Hawiger, Dendritic Cells As Inducers of Peripheral Tolerance. Trends Immunol. 38(11), 793–804 (2017)
Article
CAS
Google Scholar
M.A. Boks et al., IL-10-generated tolerogenic dendritic cells are optimal for functional regulatory T cell induction—a comparative study of human clinical-applicable DC. Clin. Immunol. 142(3), 332–342 (2012)
Article
CAS
Google Scholar
G. Flórez-Grau et al., Tolerogenic dendritic cells as a promising antigen-specific therapy in the treatment of multiple sclerosis and neuromyelitis optica from preclinical to clinical trials. Front. Immunol. (2018). https://doi.org/10.3389/fimmu.2018.01169
Article
Google Scholar
Y. Fan, J.J. Moon, Nanoparticle drug delivery systems designed to improve cancer vaccines and immunotherapy. Vaccines (2015). https://doi.org/10.3390/vaccines3030662
Article
Google Scholar
V. Dhodapkar Madhav et al., Induction of antigen-specific immunity with a vaccine targeting NY-ESO-1 to the dendritic cell receptor DEC-205. Sci. Transl. Med. (2014). https://doi.org/10.1126/scitranslmed.3008068
Article
Google Scholar
A.L. Dominguez, J. Lustgarten, Targeting the tumor microenvironment with anti-neu/anti-CD40 conjugated nanoparticles for the induction of antitumor immune responses. Vaccine 28(5), 1383–1390 (2010)
Article
CAS
Google Scholar
L.J. Cruz et al., Targeting nanoparticles to CD40, DEC-205 or CD11c molecules on dendritic cells for efficient CD8+ T cell response: a comparative study. J. Control. Release 192, 209–218 (2014)
Article
CAS
Google Scholar
A.A. Belogurov Jr. et al., Liposome-encapsulated peptides protect against experimental allergic encephalitis. FASEB J. 27(1), 222–231 (2013)
Article
CAS
Google Scholar
M.W. VonDran et al., Levels of BDNF impact oligodendrocyte lineage cells following a cuprizone lesion. J. Neurosci. 31(40), 14182 (2011)
Article
CAS
Google Scholar
Z. Hunter et al., A biodegradable nanoparticle platform for the induction of antigen-specific immune tolerance for treatment of autoimmune disease. ACS Nano 8(3), 2148–2160 (2014)
Article
CAS
Google Scholar
W. Chen et al., Immunomodulatory effects of mesenchymal stromal cells-derived exosome. Immunol. Res. 64(4), 831–840 (2016)
Article
CAS
Google Scholar
M. Maumus, C. Jorgensen, D. Noël, Mesenchymal stem cells in regenerative medicine applied to rheumatic diseases: role of secretome and exosomes. Biochimie 95(12), 2229–2234 (2013)
Article
CAS
Google Scholar
F. Tavasolian et al., miRNA-146a improves immunomodulatory effects of MSC-derived exosomes in rheumatoid arthritis. Curr. Gene Ther. 20(4), 297–312 (2020)
Article
CAS
Google Scholar
Q. Meng, B. Qiu, Exosomal MicroRNA-320a derived from mesenchymal stem cells regulates rheumatoid arthritis fibroblast-like synoviocyte activation by suppressing CXCL9 expression. Front. Physiol. (2020). https://doi.org/10.3389/fphys.2020.00441
Article
Google Scholar
J. Zheng et al., Bone marrow-derived mesenchymal stem cells-secreted exosomal microRNA-192–5p delays inflammatory response in rheumatoid arthritis. Int. Immunopharmacol. 78, 105985 (2020)
Article
CAS
Google Scholar
J. Wu et al., Mussel-inspired surface immobilization of heparin on magnetic nanoparticles for enhanced wound repair via sustained release of a growth factor and M2 macrophage polarization. ACS Appl. Mater. Interfaces. 13(2), 2230–2244 (2021)
Article
CAS
Google Scholar
L.N. Kasiewicz, K.A. Whitehead, Silencing TNFα with lipidoid nanoparticles downregulates both TNFα and MCP-1 in an in vitro co-culture model of diabetic foot ulcers. Acta Biomater. 32, 120–128 (2016)
Article
CAS
Google Scholar
T.A. Wynn, K.M. Vannella, Macrophages in tissue repair, regeneration, and fibrosis. Immunity 44(3), 450–462 (2016)
Article
CAS
Google Scholar
T.M. Raimondo, D.J. Mooney, Functional muscle recovery with nanoparticle-directed M2 macrophage polarization in mice. Proc. Natl. Acad. Sci. 115(42), 10648 (2018)
Article
CAS
Google Scholar
W. Lee et al., Thermosensitive hydrogel harboring CD146/IGF-1 nanoparticles for skeletal-muscle regeneration. ACS Appl. Bio Mater. 4(9), 7070–7080 (2021)
Article
CAS
Google Scholar
J. Ge et al., Gold and gold-silver alloy nanoparticles enhance the myogenic differentiation of myoblasts through p38 MAPK signaling pathway and promote in vivo skeletal muscle regeneration. Biomaterials 175, 19–29 (2018)
Article
CAS
Google Scholar
G. Courties et al., In vivo silencing of the transcription factor IRF5 reprograms the macrophage phenotype and improves infarct healing. J. Am. Coll. Cardiol. 63(15), 1556–1566 (2014)
Article
CAS
Google Scholar